Updated in Mar 2023: Ignore the May 2022 update, I was right all along. Microsoft actually change the default VMQ in Azure Stack HCI deployments, so that says all I need to know.
**** ALWAYS change base processor to core 2 (or 1 if HT is not enabled) **** Updated in May 2022: For about a year or so now since MS made some tweaks and a growing confidence in the out of the box settings, the optimal position has changed on WS2019.